The sexually transmitted diseases are infections being transmitted during sexual intercourse. Their frequency is increasing nowadays because of the early onset of sexual activity, the frequent switching of sexual partners and the lack of information on protection methods. The 50% of sexually transmitted infections cases occurs in the age group of 15-24 years, hence the education for adolescents and young adults for the prevention of such infections is of vital importance. Most of the sexually transmitted diseases are effectively treated with short-term antibiotic treatment (syphilis, gonococcal and non-gonococcal urethritis- chlamydia, herpes simplex) or a destruction method e.g. cryotherapy (condylomata). For other diseases (hepatitis, AIDS) there are treatment options that control the disease as not affecting the patients’ quality of life, who remain however lifelong carriers of this disease. Prevention of sexually transmitted diseases is the use of the condom as well as HPV (Human Papilloma Virus) and Hepatitis B vaccination.